Frozen Shoulder and Hormone Replacement Therapy
The purpose of this study is to determine the effects of hormone replacement therapy (HRT) in addition to standard treatment on frozen shoulder symptoms in women with age-related changes to their menstrual cycle. Frozen shoulder refers to the condition a doctor diagnosed the participant with regarding shoulder pain, st
| Condition(s) | Adhesive Capsulitis of the Shoulder, Frozen Shoulder |
|---|---|
| Status | Recruiting |
| Phase | Phase 4 |
| Study type | Interventional |
| Summary | The purpose of this study is to determine the effects of hormone replacement therapy (HRT) in addition to standard treatment on frozen shoulder symptoms in women with age-related changes to their menstrual cycle. Frozen shoulder refers to the condition a doctor diagnosed the participant with regarding shoulder pain, stiffness, and progressive loss of range of motion. Age-related menstrual cycle changes, known as perimenopause and/or menopause, refers to a change or stoppage of monthly menstrual cycles. Other symptoms participants may be experiencing include vaginal dryness, hot flashes, or night sweats. Hormone replacement therapy (HRT) refers to medicine with female hormones in it. For this study, HRT will be in the form of a patch that goes on the skin and a daily oral pill. Participants |
| Who can participate | Inclusion Criteria: * Diagnosis of adhesive capsulitis of the shoulder Exclusion Criteria: * History of hormone sensitive cancer * Bilateral adhesive capsulitis of the shoulder * Currently using hormonal treatments including contraceptives |
| Ages | 40 Years |
| Sex | Female |
| Lead sponsor | University of California, San Francisco |
| Locations | San Francisco, California, United States |
| Start date | 2026-01-15 |
| NCT ID | NCT07278323 |
| Official listing | https://clinicaltrials.gov/study/NCT07278323 |