Gait Recovery in Patients After Acute Ischemic Stroke
More than 80% of ischemic stroke (IS) patients have some walking disability, which restricts their independence in the activities of daily living. Physical therapy (PT) significantly contributes to gait recovery in patients after IS. However, it remains unclear, what type of gait training is more effective and which fa
| Condition(s) | Ischemic Stroke |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | More than 80% of ischemic stroke (IS) patients have some walking disability, which restricts their independence in the activities of daily living. Physical therapy (PT) significantly contributes to gait recovery in patients after IS. However, it remains unclear, what type of gait training is more effective and which factors may have impact on gait recovery. Two hundred fifty IS patients will be enrolled to undergo a 2-week intensive inpatient rehabilitation including randomly assigned robot-assisted treadmill gait training (RTGT) or therapist-assisted treadmill gait training (TTGT). A detailed clinical and laboratory assessment of gait quality, as well as the degree of neurological impairment, quality of life, cognition and depression will be performed in all patients during the study. We |
| Who can participate | Inclusion Criteria: * Ischemic stroke detected on magnetic resonance imaging (MRI) with NIHSS score 1-12 points at the time of enrolment * Lower limb movement impairment with a score of at least 1 point on the NIH Stroke Scale (NIHSS) at the time of enrolment * Dependency in walking according to Functional Ambulatory Category (FAC) with score interval \<1,3\> (supervision or assistance, or both, must be given in performing walking) Exclusion Criteria: * Previous history of any stroke, either ischemic or hemorrhagic * Other diseases modifying or limiting walking ability, currently receiving rehabilitation or participation in another study * Significant/symptomatic ischemic heart disease or significant/symptomatic peripheral arterial disease * Obesity (BMI ≥ 40), or weight higher than 110 kg |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Lead sponsor | University Hospital Olomouc |
| Locations | Olomouc, Czechia |
| Start date | 2020-09-01 |
| NCT ID | NCT04824482 |
| Official listing | https://clinicaltrials.gov/study/NCT04824482 |