Gestational Lifestyle & Outcomes Wellness
A Multicenter Prospective Cohort Study to Identify Risk Factors and Develop a Diagnostic Prediction Model for Gestational Diabetes Mellitus, and to Evaluate the Effectiveness of Multidisciplinary Precision Health Interventions (GLOW Plan)
| Condition(s) | GDM |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | A Multicenter Prospective Cohort Study to Identify Risk Factors and Develop a Diagnostic Prediction Model for Gestational Diabetes Mellitus, and to Evaluate the Effectiveness of Multidisciplinary Precision Health Interventions (GLOW Plan) |
| Who can participate | Inclusion Criteria: All must be met 1. Aged 18-40 years; 2. Pre-pregnancy BMI: 18.5 kg/m² \< BMI \< 28 kg/m²; 3. Able to read, understand and sign the informed consent form; 4. Receive prenatal care and deliver in the study hospital. Exclusion Criteria: Any one met leads to exclusion 1. Twin or multiple pregnancies; 2. Pre-gestational diabetes mellitus (PGDM), including new-onset diabetes during pregnancy; 3. Poorly controlled pre-pregnancy chronic hypertension (BP ≥140/90 mmHg); 4. Complicated with severe liver/kidney diseases; 5. Current/recent use of drugs affecting glucose metabolism; 6. Mental illness or severe psychological disorders; 7. Complicated with severe infection; 8. Poor compliance or refusal to use CGM/SMBG. |
| Ages | 18 Years to 40 Years |
| Sex | Female |
| Lead sponsor | The First Affiliated Hospital with Nanjing Medical University |
| Locations | Nanjing, China |
| Start date | 2025-02-25 |
| NCT ID | NCT07263412 |
| Official listing | https://clinicaltrials.gov/study/NCT07263412 |