Goat vs. Cow Milk Digestive Tolerance
The objective of this study is to assess to what extent goat's milk is better tolerated than cow's milk among individuals who report being intolerant to cow's milk, and, if so, to understand the underlying factors. To achieve this, digestive discomfort sensations and postprandial kinetics of nutrients after ingestion o
| Condition(s) | Milk Intolerance, Milk Hypersensitivity, Cow Milk Protein Sensitivity |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The objective of this study is to assess to what extent goat's milk is better tolerated than cow's milk among individuals who report being intolerant to cow's milk, and, if so, to understand the underlying factors. To achieve this, digestive discomfort sensations and postprandial kinetics of nutrients after ingestion of cow's or goat's milk will be compared in two populations: individuals intolerant to cow's milk but not to goat's milk, and individuals who show no symptoms of intolerance to either cow's or goat's milk. For this purpose, approaches based on stable isotope labeling of milk will be employed. |
| Who can participate | Inclusion Criteria: * Individuals who report being intolerant to cow milk but not to goat milk (one group) or tolerant to both cow milk and goat milk (another group) * Good general health (WHO grade = 0) * Affiliated with a social security scheme * Free, informed, and express consent, in accordance with the public health code: 'No research mentioned in 2° of Article L. 1121-1 can be conducted on a person without their free, informed, and express consent. Exclusion Criteria: * Individuals under guardianship or curatorship * Individuals under legal protection * Any known food allergies * Anemia: hemoglobin levels below 13 g/dL for men and 12 g/dL for women * Pregnant women or those likely to be (based on a positive urine pregnancy test at the time of inclusion) * Excessive alcohol consumptio |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement |
| Locations | Bobigny, France |
| Start date | 2025-09-25 |
| NCT ID | NCT07239856 |
| Official listing | https://clinicaltrials.gov/study/NCT07239856 |