High Intensity Interval Training in Chronic Stroke
Both gait and cardiovascular dysfunction are primary factors limiting community ambulation for stroke individuals. Increased gait variability and asymmetry contributes to a higher risk of falls, leading to reduced physical activity, decreased cardiorespiratory endurance, and increased walking economy and sympathetic ne
| Condition(s) | Chronic Stroke |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Both gait and cardiovascular dysfunction are primary factors limiting community ambulation for stroke individuals. Increased gait variability and asymmetry contributes to a higher risk of falls, leading to reduced physical activity, decreased cardiorespiratory endurance, and increased walking economy and sympathetic nervous system activity, thereby potentially triggering secondary strokes. Previous studies have primarily focused on the significant improvements in walking endurance and speed with high-intensity interval training (HIIT) on a treadmill, leaving a gap in understanding the effects of HIIT on oxygen uptake efficiency slope (OUES) and gait quality for stroke individuals using a stationary bicycle ergometer with exergaming. Therefore, this study aims to investigate the effects of |
| Who can participate | Inclusion Criteria: * Aged 18-69 years * At least 6 months post-stroke * Functional Ambulation Category (FAC) ≥ 3 * Mini-Mental State Examination (MMSE) ≥ 24 * Able to walk 10 meters overground with or without assistive devices Exclusion Criteria: * Unstable cardiopulmonary conditions within the last 3 months * Other chronic neurological disorders * Contraindications to exercise as recommended by the American College of Sports Medicine (ACSM) * Severe lower limb spasticity (Modified Ashworth Scale \> 2 points) * Implanted pacemaker or cardioverter defibrillator |
| Ages | 18 Years to 69 Years |
| Sex | All |
| Lead sponsor | National Yang Ming Chiao Tung University |
| Locations | Taipei, Taiwan |
| Start date | 2024-07-16 |
| NCT ID | NCT06474832 |
| Official listing | https://clinicaltrials.gov/study/NCT06474832 |