I-ASV in Cardiac Surgery
'POStoperative INTELLiVENT-adaptive support VEntilation in cardiac surgery patients II (POSITiVE II) is an investigator-initiated, international, multicenter, parallel, randomized clinical trial in patients after cardiac surgery.
| Condition(s) | Ventilator Lung |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | 'POStoperative INTELLiVENT-adaptive support VEntilation in cardiac surgery patients II (POSITiVE II) is an investigator-initiated, international, multicenter, parallel, randomized clinical trial in patients after cardiac surgery. |
| Who can participate | Inclusion Criteria: * 1\. aged \> 18 years of age; * 2\. scheduled for elective cardiac surgery; and * 3\. expected to receive postoperative ventilation in the ICU for \> 2 hours. Exclusion Criteria: 1. any emergency or semi-elective surgery (precluding informed written consent); 2. any surgery other than CABG, valve replacement or repair, or a combination (i.e., patients planned for surgery for congenital heart disease, or scheduled for heart transplantation are excluded); 3. enrolled in another interventional trail; 4. no written informed consent obtained; 5. history of recent pneumectomy or lobectomy; 6. history of COPD with oxygen at home; 7. body mass index \> 35; 8. preoperative forced expiratory volume in the first second (FeV1)/forced vital capacity (VC) \< 50% (if available); 9. p |
| Ages | 18 Years to 120 Years |
| Sex | All |
| Lead sponsor | Medical University of Vienna |
| Locations | Vienna, State of Vienna, Austria |
| Start date | 2024-05-31 |
| NCT ID | NCT06178510 |
| Official listing | https://clinicaltrials.gov/study/NCT06178510 |