Immunophenotyping in Patients With Osteoporosis
In addition to a medical history and clinical examination, the diagnosis of osteoporosis includes the measurement of bone surface density by means of dual X-ray absorptiometry (DXA). In addition, blood tests are performed for certain parameters, such as vitamin D, calcium, phosphate and C-reactive protein. In order to
| Condition(s) | Immunophenotyping Blood Samples of Patients With Osteoporosis |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | In addition to a medical history and clinical examination, the diagnosis of osteoporosis includes the measurement of bone surface density by means of dual X-ray absorptiometry (DXA). In addition, blood tests are performed for certain parameters, such as vitamin D, calcium, phosphate and C-reactive protein. In order to optimize osteoporosis diagnostics, the development of further specific methods is required. The modulation of the immune system seems promising in this respect, since osteoporosis is based on an inflammatory reaction. Various regulatory markers of the innate and acquired immune system, which seem to be relevant in the development of the disease, have already been detected in osteoporosis patients. This study may help to gain new insights into disease-associated immunoregulato |
| Who can participate | Inclusion Criteria: * Adult patients (≥ 18 years) diagnosed with osteoporosis. * Written informed consent from the patient Exclusion Criteria: * Patients without diagnosed osteoporosis * Patients without written informed consent * Patients \< 18 years old * Patients with secondary osteoporosis |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | University Hospital, Bonn |
| Locations | Bonn, Northrhine Westfalia, Germany |
| Start date | 2021-10-10 |
| NCT ID | NCT05132348 |
| Official listing | https://clinicaltrials.gov/study/NCT05132348 |