Impact of a New Bioceramic Based Intracanal Medication
Periapical lesions are the commonly occurring pathologic lesions that affect the periradicular tissues of the tooth.This lesion can be classified as granuloma, cystic, or abscess .The pathological changes seen in some periradicular and periapical cases are due to the presence of microorganisms, and their byproducts.The
| Condition(s) | Post Operative Pain |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Periapical lesions are the commonly occurring pathologic lesions that affect the periradicular tissues of the tooth.This lesion can be classified as granuloma, cystic, or abscess .The pathological changes seen in some periradicular and periapical cases are due to the presence of microorganisms, and their byproducts.These released toxins have the ability to diffuse through inflamed pulpal tissue and get into the periapical area. In a necrotic pulp, the lack of blood flow in the root prevents host immunity from eliminating the infection. |
| Who can participate | Inclusion Criteria: * Patients with mature teeth. * Patients with periapical periodontitis. * Maxillary anterior teeth only will be involved. * Patients should be free from any systemic disease that may affect normal healing and predictable outcome. * Patients who will agree to the consent and will commit to follow-up period Exclusion Criteria: * Patients with immature roots. * Patients with any systemic disease that may affect normal healing. * Patients with swelling. * Pregnant females. * Patients who could/would not participate in a 1-year follow-up. * Patients with old age. * Teeth with periodontal involvement. * Teeth with vertical root fractures. * Non-restorable teeth. * Cases with previously initiated endodontic treatment. |
| Ages | 18 Years to 40 Years |
| Sex | All |
| Lead sponsor | Minia University |
| Locations | Minya, Egypt |
| Start date | 2025-07-01 |
| NCT ID | NCT07075055 |
| Official listing | https://clinicaltrials.gov/study/NCT07075055 |