Impact of Beta-glucan Supplementation During Calorie and Carbohydrate-restricted Diet on B
This study will investigate whether beta-glucan supplementation, when added to an energy and carbohydrate-restricted diet, facilitates body weight and body fat loss, and leads to less detrimental changes in subjective appetite and gastrointestinal appetite hormones. This will be a double-blind, randomised, controlled t
| Condition(s) | Overweight and Obese Women |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | This study will investigate whether beta-glucan supplementation, when added to an energy and carbohydrate-restricted diet, facilitates body weight and body fat loss, and leads to less detrimental changes in subjective appetite and gastrointestinal appetite hormones. This will be a double-blind, randomised, controlled trial in which healthy females living with overweight and obesity will be randomly assigned to a beta-glucan or a cellulose (placebo) group (1:1 basis). The randomisation software will be used to generate a randomisation list. This list will be held by a person independent of the research team. During the 4-week intervention, participants will consume an energy and carbohydrate-restricted diet combined with 9 g/day of beta-glucan (beta-glucan group) or 9 g/day of cellulose (Pl |
| Who can participate | Inclusion Criteria: * Healthy females living with overweight or obese (BMI of 25 - 39.9 kg/m2). * Age between 18 to 60 years. * Stable body weight for at least 3 months preceding the study. Exclusion Criteria: * Smokers * Irregular menstrual cycle * Exercising more than 75min a week * Pregnant or lactating * Food allergies * Vegan or vegetarian or follow any diet other than the typical Western diet. * Taking dietary supplement at the time of the study. |
| Ages | 18 Years to 60 Years |
| Sex | Female |
| Accepts healthy volunteers | Yes |
| Lead sponsor | University of Glasgow |
| Locations | Glasgow, United Kingdom |
| Start date | 2024-07-01 |
| NCT ID | NCT07299942 |
| Official listing | https://clinicaltrials.gov/study/NCT07299942 |