Improving Access to PrEP (HIV Prevention Medication) for People in Underserved Areas of Ri
This study aims to improve access to HIV prevention using pre-exposure prophylaxis (PrEP) among underserved populations in Rio de Janeiro, including gay and bisexual men, transgender women, and sex workers. Despite the proven effectiveness of PrEP, many people at higher risk of HIV face barriers to accessing and contin
| Condition(s) | HIV Infections |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | This study aims to improve access to HIV prevention using pre-exposure prophylaxis (PrEP) among underserved populations in Rio de Janeiro, including gay and bisexual men, transgender women, and sex workers. Despite the proven effectiveness of PrEP, many people at higher risk of HIV face barriers to accessing and continuing this prevention method, especially those living in socially and economically vulnerable communities. The study will evaluate whether offering PrEP directly in community-based settings-such as non-governmental organizations, mobile health units, and through telehealth and digital tools-can increase its uptake and continued use. Participants who test negative for HIV will be offered daily oral PrEP, along with counseling and follow-up support. Those who test positive will |
| Who can participate | Inclusion Criteria: * Individuals aged 15 years or older * Gay, bisexual, and other men who have sex with men (MSM) * Transgender women and travestis * Other sexual and gender minorities (SGM) * Cisgender women in situations of social or economic vulnerability * Sex workers * Individuals seeking HIV testing and/or pre-exposure prophylaxis (PrEP) * HIV-negative at screening * Willing and interested in initiating PrEP * Eligible for PrEP according to Brazilian national guidelines Exclusion Criteria: * Positive HIV test result at screening or during study participation * Individuals not eligible for PrEP according to Brazilian national guidelines |
| Ages | 15 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Oswaldo Cruz Foundation |
| Locations | Nova Iguaçu, Rio de Janeiro, Brazil; Rio de Janeiro, Rio de Janeiro, Brazil |
| Start date | 2025-09-01 |
| NCT ID | NCT07584122 |
| Official listing | https://clinicaltrials.gov/study/NCT07584122 |