Inspiratory Muscle Training in Patients With Inflammatory Myopathy
Inflammatory myopathies are rare autoimmune diseases leading to progressive muscle weakness, often including the respiratory muscles. This study aims to investigate whether inspiratory muscle training (IMT) using a threshold device can improve functional status in patients with inflammatory myopathy. Thirty-three patie
| Condition(s) | Inflammatory Myopathies |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Inflammatory myopathies are rare autoimmune diseases leading to progressive muscle weakness, often including the respiratory muscles. This study aims to investigate whether inspiratory muscle training (IMT) using a threshold device can improve functional status in patients with inflammatory myopathy. Thirty-three patients will undergo a 3-month home-based IMT program with progressive resistance. Functional capacity, inspiratory muscle strength, lung function, diaphragmatic mobility, fatigue, and quality of life will be assessed at baseline and during follow-up. The primary hypothesis is that IMT will enhance inspiratory muscle strength and translate into better functional performance and quality of life. |
| Who can participate | Inclusion Criteria: * Diagnosis of inflammatory myopathy according to European Alliance of Associations for Rheumatology / American College of Rheumatology criteria * Age ≥ 18 years * Stable clinical condition allowing participation in physical activity * Ability to understand and follow instructions * Written informed consent to participate in the study Exclusion Criteria: * Cognitive impairment preventing proper exercise performance * Current respiratory tract infection * Previous respiratory muscle training within the last 12 months * History of spontaneous pneumothorax * Pulmonary hypertension * Tympanic membrane rupture or other middle ear pathology * Lack of voluntary and informed consent |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | Józef Piłsudski University of Physical Education |
| Locations | Warsaw, Poland |
| Start date | 2024-08-12 |
| NCT ID | NCT07274267 |
| Official listing | https://clinicaltrials.gov/study/NCT07274267 |