Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptat
The goal of this study is to learn more about the brain pathways and activity involved in creating Visual Snow Syndrome (VSS). The main questions it aims to answer are: * Does VSS arise from spontaneous activity in brain pathways? * Where in the brain does the activity contributing to VSS arise? * How does brain activi
| Condition(s) | Visual Snow Syndrome, Migraine, Healthy |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The goal of this study is to learn more about the brain pathways and activity involved in creating Visual Snow Syndrome (VSS). The main questions it aims to answer are: * Does VSS arise from spontaneous activity in brain pathways? * Where in the brain does the activity contributing to VSS arise? * How does brain activity contribute to VSS? Participants will: 1. Undergo assessments and questionnaires to understand visual and mental symptoms, cognitive, and sensory function. 2. Make visual judgements based on images presented to them both inside and outside a magnetic resonance imaging (MRI) machine. 3. Undergo scanning of their brain while inside of an MRI machine. |
| Who can participate | Inclusion Criteria for People with Visual Snow Syndrome: * Between the ages of 18 and 60 years old * Normal (20/25 or better in each eye) or corrected-to-normal vision (MR-compatible glasses will be provided as needed) * Ability to comply with study instructions * Individuals who have a current diagnosis of VSS from a neuro-ophthalmologist or meet diagnostic criteria of VSS (experience of dynamic dots across the visual field persisting longer than 3 months and at least 2 of the following additional visual symptoms: palinopsia, entoptic phenomena, trails behind moving objects, photophobia, or nyctalopia) * Individuals living in Minnesota within 2 hours of the study site Inclusion Criteria for Non-snow Controls: * Between the ages of 18 and 60 years old * Normal (20/25 or better in each eye) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | University of Minnesota |
| Locations | Minneapolis, Minnesota, United States |
| Start date | 2025-04-11 |
| NCT ID | NCT06961864 |
| Official listing | https://clinicaltrials.gov/study/NCT06961864 |