Locomotor Recovery and Compensation Post-stroke (LRC)
The proposed research will characterize of the time course of neurological and locomotor recovery as well as development of compensatory strategies throughout sub-acute and chronic phases post stroke. In addition, we will also investigate the extent to which measures of recovery and compensation are malleable and can b
| Condition(s) | Stroke |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The proposed research will characterize of the time course of neurological and locomotor recovery as well as development of compensatory strategies throughout sub-acute and chronic phases post stroke. In addition, we will also investigate the extent to which measures of recovery and compensation are malleable and can be altered with specific interventions in both the early and late stages post-stroke. Delineation of the time course of development and magnitude of patterns of recovery and compensation should result in alternative predictive "rules' regarding how patients early post-stroke could recovery functional and neurological function. |
| Who can participate | Inclusion criteria: * individuals early post-stroke (\<15-30 days) * first ever stroke * unilateral hemiparesis * currently receiving inpatient rehabilitation * ability to follow 1-step commands * provision of informed consent * medical clearance from the rehabilitation physician to participate. \\ Exclusion criteria: * uncontrolled cardiovascular, metabolic or respiratory disease that limits exercise participation (e.g., congestive heart failure, resting blood pressure \> 200/110 mmHg, uncontrolled diabetes, end-stage renal disease) * absolute criteria for termination of exercise testing during initial and repeated ECG testing during graded exercise testing using ACSM guidelines . * other orthopedic or neurological disorder that limited walking prior to stroke |
| Ages | 18 Years to 85 Years |
| Sex | All |
| Lead sponsor | Indiana University |
| Locations | Indianapolis, Indiana, United States |
| Start date | 2021-09-01 |
| NCT ID | NCT05081713 |
| Official listing | https://clinicaltrials.gov/study/NCT05081713 |