Long-Term Multidisciplinary Physiotherapy for Breast Cancer Survivors: A Randomized Contro
This multi-center randomized controlled trial (RCT) evaluates the long-term (12-month) effectiveness of a standardized multidisciplinary physiotherapy program versus standard care on persistent pain, upper limb (UL) dysfunction, and cancer-related fatigue (CRF) in breast cancer survivors. The study also examines improv
| Condition(s) | Breast Cancer, Breast Cancer Female |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | This multi-center randomized controlled trial (RCT) evaluates the long-term (12-month) effectiveness of a standardized multidisciplinary physiotherapy program versus standard care on persistent pain, upper limb (UL) dysfunction, and cancer-related fatigue (CRF) in breast cancer survivors. The study also examines improvements in quality of life and psychological well-being. The standardized intervention combines specific exercise therapy, manual therapy, education, and mind-body interventions and is designed to produce sustained benefits beyond the acute rehabilitation phase. |
| Who can participate | Inclusion Criteria: Women aged between 18 and 65 years. History of breast cancer surgery (with or without axillary lymph node dissection). Completed acute cancer treatment (surgery, chemotherapy, and/or radiation) at least 6 months prior to enrollment. Currently in the survivorship phase, with no active evidence of disease. Experiencing persistent sequelae related to treatment, such as: Moderate to severe pain (e.g., VAS score ≥ 30 on a 0-100 scale), and/or Upper limb dysfunction, and/or Cancer-related fatigue (as measured by FACIT-Fatigue). Able to understand and provide written informed consent. Exclusion Criteria: Diagnosis of recurrent or metastatic breast cancer. Currently receiving active cancer treatment (chemotherapy, radiation for active disease, or immunotherapy). Participation i |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Lead sponsor | Al Hayah University In Cairo |
| Locations | Cairo, Egypt |
| Start date | 2025-04-23 |
| NCT ID | NCT06913244 |
| Official listing | https://clinicaltrials.gov/study/NCT06913244 |