Loss of Autonomy in the Elderly: Relationships Between Gut Microbiota Diversity, Nutrition
Older adults currently make up 25% of the population in France, and future health expenditures will be largely related to the consequences of aging. Normal aging is associated with a progressive decrease in cognitive and sensorimotor function, malnutrition and/or under-nutrition and intestinal dysbiosis (i.e. changes i
| Condition(s) | Elderly Small Eater |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | Older adults currently make up 25% of the population in France, and future health expenditures will be largely related to the consequences of aging. Normal aging is associated with a progressive decrease in cognitive and sensorimotor function, malnutrition and/or under-nutrition and intestinal dysbiosis (i.e. changes in the composition and/or stability of the microbiota). Furthermore, admission to long-term care facilities such as Etablissement d'Hébergement pour Personnes Agées Dépendantes (EHPAD) leads to drastic changes in lifestyle in terms of (i) nutrition and (ii) motor functions. These modifications can influence the composition of the intestinal microbiota and its temporal evolution. We will study the relationship between the deterioration of cognitive and sensorimotor function, di |
| Who can participate | Inclusion Criteria: * Person who has given oral consent and has not objected to being included in the study, or if necessary, oral consent of an appointed legal representative. * A person over 75 years of age residing in an EHPAD who may be under guardianship or curatorship. * A person over 75 years of age with a loss of appetite (i.e. a small eater) residing in an EHPAD, who may be under guardianship or curatorship. Exclusion Criteria: * Person not affiliated to national health insurance * Elderly person with an infectious syndrome at the time of admission; * Elderly person with diarrhoea (infectious or not) at the time of admission; * Elderly person receiving recently prescribed antimicrobials at the time of admission (antibiotics or antifungals) * Elderly person with celiac disease and/ |
| Ages | 75 Years |
| Sex | All |
| Lead sponsor | Centre Hospitalier Universitaire Dijon |
| Locations | Dijon, France |
| Start date | 2023-06-13 |
| NCT ID | NCT05449119 |
| Official listing | https://clinicaltrials.gov/study/NCT05449119 |