Maternal Left Lateral Position in Fetal Growth Restriction
The goal of this clinical trial is to learn if maternal left-lateral positioning in pregnancy works to treat fetal growth restriction. This study will also help us learn about the effects of left-lateral positioning on maternal metabolomics, maternal mental health, fetal cardiac function, and delivery outcomes. The mai
| Condition(s) | Fetal Growth Restriction |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The goal of this clinical trial is to learn if maternal left-lateral positioning in pregnancy works to treat fetal growth restriction. This study will also help us learn about the effects of left-lateral positioning on maternal metabolomics, maternal mental health, fetal cardiac function, and delivery outcomes. The main questions it aims to answer are: * Does maternal left-lateral position in a pregnancy with fetal growth restriction improve the baby's growth? * How are maternal metabolomics, delivery outcomes, maternal mental health, and fetal cardiac function impacted by maternal left-lateral position? Researchers will compare the intervention group to pregnancies with fetal growth restriction that receive standard of care (without left-lateral positioning) to see if left-lateral positio |
| Who can participate | Inclusion Criteria: * Pregnant persons between 18 - 65 years of age, with a diagnosis of fetal growth restriction, with an estimated fetal weight less than tenth percentile * Participants with a singleton pregnancy between 24- and 34-weeks' gestational age * Participants with fluency in English or Spanish language Exclusion Criteria: * Patients with a known history of deep vein thrombosis, pulmonary embolism, or hypercoagulability disorder * Patients with a pre-pregnancy BMI greater than 40 * Pregnancy with severe abnormality in umbilical artery Doppler flow, including absent end-diastolic flow (AEDF) and reverse end-diastolic flow (REDF) * Patients receiving anticoagulation therapy * Pregnancy with suspected chromosomal anomalies or a multifetal pregnancy * Patients with an active smoking |
| Ages | 18 Years to 65 Years |
| Sex | Female |
| Lead sponsor | University of Colorado, Denver |
| Locations | Aurora, Colorado, United States; Denver, Colorado, United States |
| Start date | 2025-07-28 |
| NCT ID | NCT06919692 |
| Official listing | https://clinicaltrials.gov/study/NCT06919692 |