Microbiome and Atopy in Mali
This study is about allergic diseases in people living in Mali. Allergic diseases can cause health problems like asthma or skin rashes. In this study, the investigators will look for clues about things that may affect whether people get allergic diseases. The investigators will look at things on or in the body, like ge
| Condition(s) | Atopic Disease |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | This study is about allergic diseases in people living in Mali. Allergic diseases can cause health problems like asthma or skin rashes. In this study, the investigators will look for clues about things that may affect whether people get allergic diseases. The investigators will look at things on or in the body, like germs, and things in the environment, like pollution. To do this, the investigators will collect different types of biological samples, health information, and environmental information from people with allergic diseases and people without allergic diseases. The investigators will compare what is found in each group to look for differences that might be related to allergic disease. |
| Who can participate | Inclusion Criteria (Study Group): * Aged ≥3 years. * Able to provide informed consent (for ages ≥18 years) or has a parent or guardian who can provide informed consent on their behalf (for ages \<18 years). * Positive Screening questionnaire for asthma or eczema. * Diagnosed with atopic dermatitis or asthma via physician diagnosis and criteria as follows: * Clinical diagnosis of atopic disease, as defined by Hanifin and Rajka criteria, that has been present for ≥3 months before the screening visit. Inclusion Criteria (Healthy Volunteers): * Aged ≥3 years. * Able to provide informed consent (for ages ≥18 years) or has a parent or guardian who can provide informed consent on their behalf (for ages \<18 years). * Negative Screening questionnaire for asthma and eczema. * In good general health |
| Ages | 3 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | National Institute of Allergy and Infectious Diseases (NIAID) |
| Locations | Bamako, Mali; Bamako, Mali |
| Start date | 2025-09-30 |
| NCT ID | NCT07051902 |
| Official listing | https://clinicaltrials.gov/study/NCT07051902 |