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Molecular Pituitary Imaging Using 18F-FET PET

The goal of this single centre pilot study is to explore whether 18F-fluoro-ethyl-tyrosine PET (FET-PET) yields comparable findings to 11C-methionine PET (Met-PET) for the localisation of pituitary tumours.

Condition(s)Pituitary Adenoma
StatusRecruiting
PhaseNA
Study typeInterventional
SummaryThe goal of this single centre pilot study is to explore whether 18F-fluoro-ethyl-tyrosine PET (FET-PET) yields comparable findings to 11C-methionine PET (Met-PET) for the localisation of pituitary tumours.
Who can participateInclusion criteria * Participant is willing and able to give informed consent for participation in the study * Male or female, age 18 or above * Presence of pituitary adenoma suspected on the basis of clinical/biochemical and/or radiological findings * Previous 11C-Met-PET/CT Exclusion criteria * Inability to give informed consent * Pregnancy or suspected pregnancy * Inability to lie supine for 30-60 minutes * Patient body habitus above scanner dimensions * Known allergy to intravenous radiographic contrast agents
Ages18 Years to 100 Years
SexAll
Lead sponsorUniversity of Cambridge
LocationsCambridge, Cambridgeshire, United Kingdom
Start date2024-09-03
NCT IDNCT06584123
Official listinghttps://clinicaltrials.gov/study/NCT06584123

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