Mucosal and Microbiota Changes During Acute Campylobacteriosis
Gastrointestinal (GI) infection with Campylobacter causes inflammation in the bowel and can change bacteria in the gut. Certain individuals with Campylobacter infection are also known to develop chronic bowel problems such as Irritable Bowel Syndrome (IBS). The researchers are doing this study to understand if changes
| Condition(s) | Irritable Bowel Syndrome |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | Gastrointestinal (GI) infection with Campylobacter causes inflammation in the bowel and can change bacteria in the gut. Certain individuals with Campylobacter infection are also known to develop chronic bowel problems such as Irritable Bowel Syndrome (IBS). The researchers are doing this study to understand if changes in gut bacteria and gut mucosal lining during an acute infection can help identify individuals who might be at risk for developing problems in the future. |
| Who can participate | Inclusion Criteria: * No abdominal surgery (except appendectomy and cholecystectomy) * Stool culture or Polymerase chain reaction (PCR) positive enteritis with Campylobacter Exclusion Criteria: * History of IBS, Irritable Bowel Disease (IBD) (Crohn's disease or ulcerative colitis), microscopic colitis or celiac disease. * History of gastroenteritis in six months prior to Campylobacter enteritis * Pregnancy |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Lead sponsor | Mayo Clinic |
| Locations | Rochester, Minnesota, United States |
| Start date | 2014-10-31 |
| NCT ID | NCT03223077 |
| Official listing | https://clinicaltrials.gov/study/NCT03223077 |