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Multicenter Study for the Validation of an AI-based ECG Platform for Early Cardiac Amyloid

CONCERTO is a retrospective, observational, multicentric and single-arm study to perform an external validation of the cloud-based and AI-powered electrocardiogram (ECG) analysis platform, named Willem™, to detect Transthyretin cardiac amyloidosis (ATTR-CA). Thus, this study will assess Willem™ ability to distinguish b

Condition(s)Transthyretin Cardiac Amyloidosis
StatusRecruiting
Study typeObservational
SummaryCONCERTO is a retrospective, observational, multicentric and single-arm study to perform an external validation of the cloud-based and AI-powered electrocardiogram (ECG) analysis platform, named Willem™, to detect Transthyretin cardiac amyloidosis (ATTR-CA). Thus, this study will assess Willem™ ability to distinguish between truly diagnosed ATTR-CA patients and confirmed non-ATTR-CA patients from ECG data.
Who can participateInclusion Criteria: * Subjects ≥ 18 years old * Subjects with 12-leads ECG records with a 10 seconds minimum length on digital format Exclusion Criteria: * Patients with paced rhythm on the ECG.
Ages18 Years
SexAll
Lead sponsorIdoven 1903 S.L.
LocationsEvanston, Illinois, United States; Toulouse, France; Bonn, Germany; Bologna, Italy; Florence, Italy; Trieste, Italy (+4 more sites)
Start date2025-05-27
NCT IDNCT06978660
Official listinghttps://clinicaltrials.gov/study/NCT06978660

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