Multidimensional Evaluation of Patients' Affected by Obstructive Apnea Syndrome (OSAS) Bef
This observational study aims to evaluate multiple dimensions of health in patients with Obstructive Sleep Apnea Syndrome (OSAS), before and after three weeks of ventilotherapy. Specifically, the study aims to identify pre- vs post-treatment differences in the following domains: * cognitive performance * blood expressi
| Condition(s) | Obstructive Sleep Apnea, Sleep Disorder, Well-Being, Psychological, Cognitive Impairment, Cognitive Change, Neurologic Signs |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | This observational study aims to evaluate multiple dimensions of health in patients with Obstructive Sleep Apnea Syndrome (OSAS), before and after three weeks of ventilotherapy. Specifically, the study aims to identify pre- vs post-treatment differences in the following domains: * cognitive performance * blood expression of biomarkers related to neurodegeneration * psychosocial wellbeing Thus, patients will complete the following evaluations before (T0) and after (T1) ventilotherapy: * neuropsychological standard assessment * blood sampling * psychosocial self-reported questionnaires |
| Who can participate | Inclusion Criteria: * OSAS diagnosis (AHI \> 5) * handedness: right Exclusion Criteria: * previous ventilotherapy * neurological and/or neurodegenerative conditions * Personality disorders, autism spectrum disorders, schizophrenia, psychosis * sleep disorders comorbidities (eg., narcolepsy) |
| Ages | 20 Years to 60 Years |
| Sex | All |
| Lead sponsor | Istituto Auxologico Italiano |
| Locations | Piancavallo, VCO, Italy |
| Start date | 2024-02-29 |
| NCT ID | NCT06312956 |
| Official listing | https://clinicaltrials.gov/study/NCT06312956 |