Myocardial Ischemia Without Obstructive Coronary Stenoses
Coronary-related myocardial ischemia can result from obstructive epicardial stenosis or non-obstructive causes including coronary microcirculatory dysfunction and vasomotor disorders. This prospective study has been created in order to provide knowledge in the field of non-obstructive coronary artery disease.
| Condition(s) | Myocardial Ischemia, Non-Obstructive Coronary Atherosclerosis, Microvascular Coronary Artery Disease, Vasospastic Angina, Myocardial Bridging |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | Coronary-related myocardial ischemia can result from obstructive epicardial stenosis or non-obstructive causes including coronary microcirculatory dysfunction and vasomotor disorders. This prospective study has been created in order to provide knowledge in the field of non-obstructive coronary artery disease. |
| Who can participate | Inclusion Criteria: * Written informed consent available. * Age ≥ 18 years. * Patient eligible for invasive physiological assessment with adenosine and / or acetylcholine. Exclusion Criteria: * Hemodynamic instability. * Anticipated technical issues for physiology wire measurements. * Culprit vessel of acute coronary syndrome * Contraindications for adenosine administration. * Contraindications for acetylcholine test. * Reduced life expectancy (less than 1 year). |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | Hospital San Carlos, Madrid |
| Locations | Madrid, Spain |
| Start date | 2017-11-08 |
| NCT ID | NCT04827498 |
| Official listing | https://clinicaltrials.gov/study/NCT04827498 |