Neonate Cerebral Activity in Immediate Post Partum
Neonatal anoxia-ischemia causes significant neurodevelopmental disorders. In this study the investigators want to better understand the interactions between the nervous and the hemodynamic cerebral systems during the adaptation of the neonate to ectopic life just after birth. Birth is an at risk situation of neonatal a
| Condition(s) | Anoxia-Ischemia, Brain, Neonatal Encephalopathy |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Neonatal anoxia-ischemia causes significant neurodevelopmental disorders. In this study the investigators want to better understand the interactions between the nervous and the hemodynamic cerebral systems during the adaptation of the neonate to ectopic life just after birth. Birth is an at risk situation of neonatal anoxic ischemia and the lack of objective criteria for cerebral tissue oxygenation has consequences on neuronal activity. Ph cord analysis is inadequate and only indirectly reflects the state of cerebral oxygenation. Both neuronal and vascular systems are part of the same functional entity and the analysis of their interactions is likely to reveal some early malfunctions of these networks. In this study, the investigators want to develop a multi-scale, multimodal approach that |
| Who can participate | Inclusion Criteria: * Full term neonates between 36 and 41 weeks Gestational Age Exclusion Criteria: * Premature neonates * Neonates of twin pregnancy * Suspicion of congenital malformation seen in antenatal ultrasound * Any pathology requiring pediatric care from birth * Newborns whose mothers had a chronic viral infection such as AIDS, hepatitis B or C, or who had a multidrug-resistant bacteria |
| Ages | 1 Minute to 15 Minutes |
| Sex | All |
| Lead sponsor | Centre Hospitalier Universitaire, Amiens |
| Locations | Amiens, France |
| Start date | 2021-03-03 |
| NCT ID | NCT04225975 |
| Official listing | https://clinicaltrials.gov/study/NCT04225975 |