Neuromuscular Electrical Stimulation in a Patient on Invasive Mechanical Ventilation (MOVC
This clinical study aims to compare the effects of conventional physical therapy alone versus conventional physical therapy combined with neuromuscular electrical stimulation (NMES) in patients admitted to the ICU and undergoing invasive mechanical ventilation. Participants will be randomly assigned to receive either c
| Condition(s) | Mechanical Ventilation, Critical Illness, Intensive Care Unit Patients, Muscle Weakness Condition, Neuromuscular Electrical Stimulation (NMES) |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | This clinical study aims to compare the effects of conventional physical therapy alone versus conventional physical therapy combined with neuromuscular electrical stimulation (NMES) in patients admitted to the ICU and undergoing invasive mechanical ventilation. Participants will be randomly assigned to receive either conventional physical therapy or the same therapy plus NMES applied to the lower limbs. The protocol includes muscle-specific stimulation parameters and safety criteria to postpone sessions in cases of clinical instability. The primary goal is to assess whether NMES improves muscle function and recovery in critically ill patients. |
| Who can participate | Inclusion Criteria: * Patients will be eligible if they are 18 years or older, are under invasive mechanical ventilation (IMV), and are expected to require IMV for more than 48 hours. Exclusion Criteria: * Body mass index (BMI) greater than or equal to 35 kg/m²; * Length of ICU stay longer than 7 ICU-free days or more than 3 continuous days of invasive mechanical ventilation (IMV) before enrollment; * Known intracranial process (e.g., stroke, intracranial hypertension); * Neuromuscular disease (e.g., Guillain-Barré syndrome, myasthenia gravis) at ICU admission; * Inability to speak Portuguese or pre-existing cognitive impairment prior to ICU admission; * Any condition that prevents neuromuscular electrical stimulation (NMES) treatment or assessment of the primary outcome in both legs (e.g. |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | Hospital Moinhos de Vento |
| Locations | Porto Alegre, Rio Grande do Sul, Brazil |
| Start date | 2025-09-04 |
| NCT ID | NCT07188350 |
| Official listing | https://clinicaltrials.gov/study/NCT07188350 |