Non-invasive Vagus Nerve Stimulation (nVNS) and Cognition in Young Adult Vapers - A Pilot
The purpose of this study is to assess the effects of non-invasive vagus nerve stimulation (nNVS) on cognitive functioning in the users of e-cigarettes or vaping products. The investigators will use a digital wellness companion product (TRUVAGA™ device) that provides mild transcutaneous nVNS. The participants will be r
| Condition(s) | Vaping |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The purpose of this study is to assess the effects of non-invasive vagus nerve stimulation (nNVS) on cognitive functioning in the users of e-cigarettes or vaping products. The investigators will use a digital wellness companion product (TRUVAGA™ device) that provides mild transcutaneous nVNS. The participants will be randomized to receive either a 2-min nNVS stimulation or control stimulation in the neck region followed by completion of three cognitive tests of attention and executive function. |
| Who can participate | Inclusion Criteria: * Healthy young adults * Age range 18-25 years * Current or prior users of e-cigarettes Exclusion Criteria: Participants will be excluded from the study if they: * Have any rash, infection, swelling, cut, soreness, drug patch, surgical scar on the neck area * Have any implantable medical device in their body such as a pacemaker, hearing aid implant, or any other metallic/electronic device * Have any hearing or vision problems that are not corrected * Are pregnant or breastfeeding * Have any learning disabilities * Have a medical history of any of the following condition * Meningitis * Traumatic brain injury * Seizure * Syncope * Schizophrenia * Schizoaffective disorder * Bulimia (eating disorder) * Other serious neurological illness * Have a medical history of any of th |
| Ages | 18 Years to 25 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Temple University |
| Locations | Philadelphia, Pennsylvania, United States |
| Start date | 2025-03-18 |
| NCT ID | NCT06804109 |
| Official listing | https://clinicaltrials.gov/study/NCT06804109 |