Non-pharmacological Prevention of POD in Frailty Elderly Undergoing Elective Surgery Appli
The increase in the population over 60 years of age who could receive surgery due to changes in life expectancy and advances in surgical and anesthetic techniques. Likewise, elderly people (EP) may have a higher risk of postoperative morbidity and mortality compared to young people, with frailty being one of the risk f
| Condition(s) | Frail Elderly Syndrome, Primary Prevention, Postoperative Delirium, Frailty |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The increase in the population over 60 years of age who could receive surgery due to changes in life expectancy and advances in surgical and anesthetic techniques. Likewise, elderly people (EP) may have a higher risk of postoperative morbidity and mortality compared to young people, with frailty being one of the risk factors that increases adverse outcomes in this period and increases the probability of developing syndromes such as postoperative delirium (POD). Assessment of frailty in EP prior to surgery is not routine, so it is unknown how many frail and/or pre-frail EP undergo surgery in health care systems. There is an association between being frail and developing greater delirium and/or postoperative cognitive deficit, which in summary translates into an increase in perioperative mor |
| Who can participate | Inclusion Criteria: * Patients older than 65 years * Elective non-cardiac surgery * General anesthesia with Bilateral BIS electroencephalographic monitoring or SedLine * ASA I, II or III. Exclusion Criteria: * Neurosurgical patients * History of alcohol and/or drug abuse * History of recreational psychoactive drug use * Allergy to anesthetic drugs. |
| Ages | 65 Years |
| Sex | All |
| Lead sponsor | Pontificia Universidad Catolica de Chile |
| Locations | Santiago, Santiago Metropolitan, Chile |
| Start date | 2024-04-01 |
| NCT ID | NCT05993754 |
| Official listing | https://clinicaltrials.gov/study/NCT05993754 |