Normative Database of Healthy Subject Vascular Density Using Spectralis Heidelberg® Optica
Optical coherence tomography angiography (OCT-A) is a determinant progress to study retinal and choroidal vasculature without using a dye injection. OCT-A yields interesting results in different pathologies such as diabetes mellitus, age-related macular degeneration, hypertension blood pressure, particularly by affecti
| Condition(s) | Optical Coherence Tomography, Optical Coherence Tomography Angiography |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Optical coherence tomography angiography (OCT-A) is a determinant progress to study retinal and choroidal vasculature without using a dye injection. OCT-A yields interesting results in different pathologies such as diabetes mellitus, age-related macular degeneration, hypertension blood pressure, particularly by affecting vascular density. Normative database are necessary to compare OCT-A parameters between patients and controls. However, OCT-A devices from different manufactures may give different values for the same subject. It seems to be obvious that each OCT-A device should have its own normative database. In the literature, OCT-A normative databases are developing using different types of devices, but none is available for Heidelberg OCT-A in Caucasians. The purpose of this project is |
| Who can participate | Inclusion Criteria: * Voluntary adult subjects or legal representative consenting for minor or subjects under protection * Intra ocular pression ≤ 21mmHg * Spherical refraction comprised between - 6 D and +6 D and/or axial length between 21 and 26mm * Patient affiliated to social security system Exclusion Criteria: * Ocular diseases: glaucoma, retinal diseases as diabetic retinopathy, age-related macular degeneration, amblyopia, optic neuropathy * Diabetes mellitus * Uncontrolled hypertension blood pressure (\> 140/90) * Recent ocular surgery (\< 6 months) * Any ophthalmological conditions interfering with a good ocular examination or OCT quality (cataract, corneal opacity …) * OCT-A sufficient quality ≥ 25 (0 = bad quality /40 = excellent quality * Not consenting patient * Pathological si |
| Ages | 18 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Centre Hospitalier Universitaire, Amiens |
| Locations | Amiens, France |
| Start date | 2023-06-12 |
| NCT ID | NCT06043622 |
| Official listing | https://clinicaltrials.gov/study/NCT06043622 |