Observational Study to Observe Variations of Gait Parameters in Patients With Neuromuscula
This study has the general objective of observing walking parameters during a clinical test to objectively estimate fatigue in patients with neuromuscular diseases. Furthermore, the investigators want to evaluate the feasibility of collecting physical activity in daily life conditions during a one-week monitoring perio
| Condition(s) | Muscular Dystrophies, Myopathies, Spinal Muscular Atrophy (SMA), Charcot Marie Tooth Disease |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | This study has the general objective of observing walking parameters during a clinical test to objectively estimate fatigue in patients with neuromuscular diseases. Furthermore, the investigators want to evaluate the feasibility of collecting physical activity in daily life conditions during a one-week monitoring period using a wearable sensor. |
| Who can participate | Inclusion Criteria: * Ambulant adult patients with genetic diagnosis of muscular dystrophy/myopathy (dystrophinopathies, muscular dystrophies and congenital and non-congenital myopathies), of spinal muscular atrophy (SMA) and with molecular diagnosis of Charcot-Marie Tooth 1 or 2. * independent walking, even with assistance; Exclusion Criteria: * Dilated or ischemic heart disease with moderate impairment; * Chronic respiratory failure: forced vital capacity (FVC) \< 40%; more than 5% of nocturnal time spent with peripheral oxygen saturation levels \< 90. |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | IRCCS Eugenio Medea |
| Locations | Bosisio Parini, Lecco, Italy; Conegliano, Treviso, Italy |
| Start date | 2017-10-27 |
| NCT ID | NCT06666816 |
| Official listing | https://clinicaltrials.gov/study/NCT06666816 |