Omega-3 Fatty Acids and Nutritional Support in Gastrointestinal Cancer
Sarcopenia is a frequent complication in patients with cancer and chronic diseases, it is characterized by decreased muscle strength and fatigue due to reduced skeletal muscle mass, which is accompanied by atrophy and decreased quality of muscle tissue. In all cases, it negatively impacts treatment tolerance, clinical
| Condition(s) | Sarcopenia |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Sarcopenia is a frequent complication in patients with cancer and chronic diseases, it is characterized by decreased muscle strength and fatigue due to reduced skeletal muscle mass, which is accompanied by atrophy and decreased quality of muscle tissue. In all cases, it negatively impacts treatment tolerance, clinical outcomes and survival, in consequence, quality of life of these patients decreases while morbidity, mortality and costs increase. In this context, appropriate nutritional screening and early nutrition support are extremely recommended, to this aim, in some cases, oral nutritional supplements (ONS) are necessary; ONS could have a standard formula or be enriched with specific nutrients (arginine, glutamine, branched chain amino acids, n-3 fatty acids, and nucleotides), which ca |
| Who can participate | Inclusion Criteria: * \- Patients with Gastrointestinal tumor undergoing systemic treatment (chemo-radio-immuno therapy or their combination) * Body weight loss \>5% in the previous three months or \>10% in the previous six months * Both sexes * Age between 18-85 y-old. Exclusion Criteria: * Life expectancy \< 2 weeks * MDRD \< 15 mL/min * End-stage liver disease * Any musculoskeletal, cardiovascular and/or neurological disorders that could affect exercising. |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | Maimónides Biomedical Research Institute of Córdoba |
| Locations | Córdoba, Cordoba, Spain |
| Start date | 2023-07-01 |
| NCT ID | NCT06015971 |
| Official listing | https://clinicaltrials.gov/study/NCT06015971 |