Omics Sequencing of Specimen Derived From Mother-Infant-Pairs
The investigators aim to collect breast-milk and feces from the participants, and apply culture techniques as well as omics sequencing technology to probe into the microbial and metabolomic signature of the specimens.
| Condition(s) | Healthy, Breast-milk Collection, Feces |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | The investigators aim to collect breast-milk and feces from the participants, and apply culture techniques as well as omics sequencing technology to probe into the microbial and metabolomic signature of the specimens. |
| Who can participate | Inclusion Criteria: * healthy pregnant women aged between 20y and 40y. * Vaginal birth * BMI\<23.5 before pregnancy * Infants' birth weight, between 2500g and 4000g. Exclusion Criteria: * gestational diabetes * diagnosis of depressive disorder during pregnancy * gestational hypertension * diagnosis of other diseases during pregnancy * Under probiotics or antibiotic treatment from 3 months prior to pregnancy till 3 months after delivery * histrory of smoking and drinking alcohol * history of diarrhea from 3 months prior to pregnancy till 3 months after delivery |
| Ages | 40 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Zhujiang Hospital |
| Locations | Guangzhou, Guangdong, China |
| Start date | 2021-06-22 |
| NCT ID | NCT05462366 |
| Official listing | https://clinicaltrials.gov/study/NCT05462366 |