Once Weekly Infant Corticosteroid Trial for DMD
The hypothesis tested here is that a lower dose of intermittent oral corticosteroids (5mg/kg/week) will be equally effective to the 10mg/kg/week dose.
| Condition(s) | Duchenne Muscular Dystrophy |
|---|---|
| Status | Recruiting |
| Phase | Phase 4 |
| Study type | Interventional |
| Summary | The hypothesis tested here is that a lower dose of intermittent oral corticosteroids (5mg/kg/week) will be equally effective to the 10mg/kg/week dose. |
| Who can participate | Inclusion Criteria: * Subjects ages 1 month through 30 months * Weakness consistent with Duchenne on exam, creatine kinase ≥ 20 times the upper limit of normal, and genetic mutation known to be causative for DMD. Exclusion Criteria: * Prior treatment with Glucocorticosteroids |
| Ages | 1 Month to 30 Months |
| Sex | Male |
| Lead sponsor | Anne M. Connolly |
| Locations | Chicago, Illinois, United States; Cincinnati, Ohio, United States; Columbus, Ohio, United States; Dallas, Texas, United States |
| Start date | 2021-04-30 |
| NCT ID | NCT05412394 |
| Official listing | https://clinicaltrials.gov/study/NCT05412394 |