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Optimizing Proton Pump Inhibitors (PPI) Prescribing With EHR-Based Decision Support

The proposed study is a quality improvement initiative designed to rigorously evaluate new variations of UCLA Health's proton pump inhibitor (PPI) order panels, building on internal quality improvement efforts to optimize prescribing workflows within the Electronic Health Record (EHR). PPIs are notoriously overprescrib

Condition(s)Prescribing Patterns, Physician, Physician's Practice Patterns, Drug Utilization Review
StatusRecruiting
PhaseNA
Study typeInterventional
SummaryThe proposed study is a quality improvement initiative designed to rigorously evaluate new variations of UCLA Health's proton pump inhibitor (PPI) order panels, building on internal quality improvement efforts to optimize prescribing workflows within the Electronic Health Record (EHR). PPIs are notoriously overprescribed, and the study team has identified that the CareConnect default prescription setting of 90 days with three refills (360 pill days) exceed standard guidelines (in most cases, 60 pill days). It is unclear whether this is the most appropriate workflow. Given that deprescribing PPIs carries minimal risk for most patients, this initiative will assess whether modifying defaulted prescription lengths influences prescribing behavior while ensuring physicians retain full decision-m
Who can participateInclusion Criteria: * UCLA Health primary care physicians who have a clinical full-time equivalency of at least 25%. Exclusion Criteria: * Physicians with a clinical full-time equivalency of less than 25%
Ages50 Years
SexAll
Lead sponsorUniversity of California, Los Angeles
LocationsLos Angeles, California, United States
Start date2026-06
NCT IDNCT06998966
Official listinghttps://clinicaltrials.gov/study/NCT06998966

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