Optimizing Recruitment to Drive Equitable Research Opportunity in Stroke Rehabilitation Tr
Stroke is a major health issue in Canada. Stroke affects over 400,000 Canadians, and this number is expected to nearly double by 2038. Research studies in stroke recovery can help us better understand effective rehabilitation treatments and help reduce the burden of stroke. Some groups of people however are commonly no
| Condition(s) | Stroke |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Stroke is a major health issue in Canada. Stroke affects over 400,000 Canadians, and this number is expected to nearly double by 2038. Research studies in stroke recovery can help us better understand effective rehabilitation treatments and help reduce the burden of stroke. Some groups of people however are commonly not included in stroke studies. For example, it is more common for men to take part in research than women, and people with aphasia (a language impairment commonly seen after stroke) are often excluded from studies. Also, deciding whether to even take part in a research study can be difficult and overwhelming, especially in the early days after stroke, leaving many people to decline to participate. Research has shown that women experience different barriers to participating in |
| Who can participate | Inclusion Criteria: 1. Primary ischemic anterior circulation stroke 2. Age ≥18 years 3. ≥5 days but \<8 weeks after stroke on the date of medication (Maraviroc or placebo) start 4. Hemiparesis requiring inpatient rehabilitation 5. Assistance available for daily rehabilitation training practice and for transportation when needed 6. Adequate language skills to understand Informed Consent and retain information during daily therapies 7. At least one of the following: some shoulder abduction with gravity eliminated and visible extension in two or more digits OR visible hip flexion or extension Exclusion Criteria: 1. Pre-stroke modified Rankin score ≥2 2. Limited resources or illness that will not enable a return to living outside of a facility 3. History of dementia 4. History of hepatitis or |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | McMaster University |
| Locations | Calgary, Alberta, Canada; Vancouver, British Columbia, Canada; Halifax, Nova Scotia, Canada; London, Ontario, Canada; Toronto, Ontario, Canada |
| Start date | 2025-06-16 |
| NCT ID | NCT06576089 |
| Official listing | https://clinicaltrials.gov/study/NCT06576089 |