Paravertebral Muscles Assessment Using High-resolution MRI in Idiopathic or Neuromuscular
Scoliosis is a common three-dimensional spinal deformity defined by vertebral rotation. Apart from collapse scoliosis, clinical and radiological similarities have been observed in children with secondary scoliosis of neuromuscular origin and children with idiopathic scoliosis in terms of the location and type of curvat
| Condition(s) | Scoliosis, Scoliosis Idiopathic, Scoliosis Neuromuscular |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Scoliosis is a common three-dimensional spinal deformity defined by vertebral rotation. Apart from collapse scoliosis, clinical and radiological similarities have been observed in children with secondary scoliosis of neuromuscular origin and children with idiopathic scoliosis in terms of the location and type of curvature. It seems relevant to study the axial musculature in these children in more detail, particularly the deep muscles (transversospinales muscles) that have a stabilising and rotational function (multifidi and rotatores). MRI is a non-invasive, non-irradiating technique used in the aetiological diagnosis of idiopathic scoliosis before adolescence and in the diagnosis of secondary scoliosis. However, the muscles are not specifically studied during these examinations. They are |
| Who can participate | Inclusion Criteria: * Children and adolescents aged 10 to 17 years old, * Scoliosis (idiopathic or neuromuscular) that is not collapsing * Cobb angle \<40° * Female preferred * Patient able to walk * Average or low BMI \<20kg/m2 * Signature of informed consent by legal guardians * Affiliation with a social security scheme (beneficiary or dependent). Exclusion Criteria: * Refusal of the patient and/or parents to participate in the study * Inability to cooperate * Subject with a contraindication to MRI * History of spinal surgery * Not affiliated with a social security scheme (beneficiary or entitled person) |
| Ages | 10 Years to 17 Years |
| Sex | All |
| Lead sponsor | Assistance Publique - Hôpitaux de Paris |
| Locations | Garches, France |
| Start date | 2025-07-17 |
| NCT ID | NCT07135765 |
| Official listing | https://clinicaltrials.gov/study/NCT07135765 |