Physical and Psychosocial Parameters in Takayasu Arteritis and Behçet's Disease: A Compara
Systemic vasculitis refers to a group of rare diseases characterized by inflammation of blood vessel walls, which may cause ischemia and structural damage in various organs. Among large-vessel vasculitides, Takayasu arteritis primarily affects the aorta and its main branches, whereas Behçet's disease is a variable vess
| Condition(s) | Takayasu Arteritis, Behçet's Disease, Healthy Controls |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | Systemic vasculitis refers to a group of rare diseases characterized by inflammation of blood vessel walls, which may cause ischemia and structural damage in various organs. Among large-vessel vasculitides, Takayasu arteritis primarily affects the aorta and its main branches, whereas Behçet's disease is a variable vessel vasculitis involving arteries and veins of all sizes. Both conditions can lead to multisystemic involvement and significantly impact physical and psychosocial health. This observational, case-control study aims to compare multiple physical and psychosocial parameters among individuals with Takayasu arteritis, Behçet's disease, and healthy controls. Assessments will include respiratory and peripheral muscle strength, functional status, exercise capacity, body composition, q |
| Who can participate | Inclusion Criteria: Inclusion Criteria (Takayasu Arteritis Group): * Age 18 years or older. * Diagnosis of Takayasu arteritis according to the American College of Rheumatology (ACR) classification criteria. * Voluntary participation with written informed consent. Inclusion Criteria (Behçet's Disease Group): * Age 18 years or older. * Diagnosis of Behçet's disease according to the International Study Group for Behçet's Disease criteria. * Voluntary participation with written informed consent. Inclusion Criteria (Healthy Control Group): * Age 18 years or older. * No history of systemic, rheumatologic, or chronic inflammatory disease. * Voluntary participation with written informed consent. Exclusion Criteria: Exclusion Criteria (Patient Groups - Takayasu Arteritis and Behçet's Disease): * Pr |
| Ages | 18 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | ÖZLEM NUR TOK YAMAN |
| Locations | Denizli, Denizli, Turkey (Türkiye) |
| Start date | 2025-09-11 |
| NCT ID | NCT07276087 |
| Official listing | https://clinicaltrials.gov/study/NCT07276087 |