Pilot Study of Personalized Aperiodic Transcranial Alternating Current Stimulation in Ante
The purpose of this study is to develop the safety, feasibility, and tolerability of a personalized transcranial alternating current stimulation (tACS) approach in antenatal depression.
| Condition(s) | Antenatal Depression, Major Depressive Disorder, Major Depressive Disorder in Pregnancy, Healthy Controls |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The purpose of this study is to develop the safety, feasibility, and tolerability of a personalized transcranial alternating current stimulation (tACS) approach in antenatal depression. |
| Who can participate | Inclusion Criteria: In order to be eligible to participate in this study, an individual must meet all of the following criteria: * Female aged 18 - 45 * Capacity to understand all relevant risks and potential benefits of the study as determined by study staff (provision of informed consent) * Stated willingness to comply with all study procedures and availability for the duration of the study * Low suicide risk (defined for this study as no active suicidal ideation in the past month and no suicide attempts, preparatory actions, or significant non-suicidal self-harm in the previous 2 years). Risk will be assessed utilizing the C-SSRS screen and triage version with further exploration of positive responses. For healthy control population: * Use of highly effective contraception for at least |
| Ages | 18 Years to 45 Years |
| Sex | Female |
| Accepts healthy volunteers | Yes |
| Lead sponsor | University of North Carolina, Chapel Hill |
| Locations | Chapel Hill, North Carolina, United States |
| Start date | 2025-08-12 |
| NCT ID | NCT06979154 |
| Official listing | https://clinicaltrials.gov/study/NCT06979154 |