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Plasmodium Immunotherapy for Advanced Cancers

The purpose of this study is to evaluate the safety of Plasmodium immunotherapy and preliminarily evaluate the effectiveness of Plasmodium immunotherapy for advanced cancers.The treatment will last 3-6 months from the day of successful infection and will be terminated by antimalarial drugs.

Condition(s)Advanced Cancers
StatusRecruiting
PhasePhase 1, Phase 2
Study typeInterventional
SummaryThe purpose of this study is to evaluate the safety of Plasmodium immunotherapy and preliminarily evaluate the effectiveness of Plasmodium immunotherapy for advanced cancers.The treatment will last 3-6 months from the day of successful infection and will be terminated by antimalarial drugs.
Who can participateInclusion Criteria: * 18-70 years of age, male or female. * Patients with advanced cancer confirmed by histopathology and imaging; and imaging lesions of the tumor are clear and measurable, including but not limited to colon cancer, breast cancer, liver cancer, lung cancer, gastric cancer,sarcoma and other solid tumors (except for nasopharyngeal carcinoma, lymphatic cancer, cervical cancer and melanoma). * The time interval of the termination of chemotherapy (including interventional chemotherapy) or radiotherapy is at least 3 months for patients who had received chemotherapy (including interventional chemotherapy) or radiotherapy; at least 5 half-life for patients who had received targeted drug therapy (the half-life of targeted drug is according to the drug instructions); * All the patie
Ages18 Years to 70 Years
SexAll
Lead sponsorCAS Lamvac Biotech Co., Ltd.
LocationsGuangzhou, Guangdong, China
Start date2017-11-23
NCT IDNCT03375983
Official listinghttps://clinicaltrials.gov/study/NCT03375983

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