Platelet Expression of FcγRIIa and Arterial Hemodynamics to Predict Recurrent Stroke in In
An observational study to determine if individuals with increased platelet FcyRIIa will have a higher risk of ischemic events.
| Condition(s) | Stroke, TIA, Ischemic Stroke, Ischemic |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | An observational study to determine if individuals with increased platelet FcyRIIa will have a higher risk of ischemic events. |
| Who can participate | Inclusion Criteria: * Stroke is defined as symptoms lasting \>24 hours and associated with imaging evidence of acute ischemia in the distribution of the stenotic vessel on head CT or brain MRI. Minor stroke is defined as NIHSS\<6, as used in prior studies. * Eligible TIA, defined as transient neurological symptoms lasting \<24 hours, need to be: a) accompanied by DWI abnormalities in the distribution of the stenotic artery; or b) multiple (\>1), stereotyped events associated with unequivocal ischemic symptoms (i.e. weakness, aphasia, diplopia), and attributed to the symptomatic artery. The intent of these restrictive inclusion criteria for TIA is to exclude potential stroke mimics. * ICAD should involve the intracranial carotid, middle cerebral, intracranial vertebral or basilar arteries. |
| Ages | 30 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | University of California, Los Angeles |
| Locations | Los Angeles, California, United States |
| Start date | 2022-09-30 |
| NCT ID | NCT05518305 |
| Official listing | https://clinicaltrials.gov/study/NCT05518305 |