Platelet Volunteers, Longitudinal and Multi-omic Study
Background: Platelets are a type of blood cell that play a critical role in bleeding, forming blood clots, and healing. Researchers want to know more about platelets work in healthy people. They want to look at how platelets clump together, how blood clots, and how genes and proteins work. They also want to study how t
| Condition(s) | Thrombosis |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | Background: Platelets are a type of blood cell that play a critical role in bleeding, forming blood clots, and healing. Researchers want to know more about platelets work in healthy people. They want to look at how platelets clump together, how blood clots, and how genes and proteins work. They also want to study how these processes change over time and how they are affected by factors such diet, exercise, weight, and new health problems. Objective: To study how platelets function in healthy people. Eligibility: Healthy people aged 18 years and older. Design: Researchers will review participants medical history. They will ask about the participant s family history and any drugs they take. Participants will have a clinic visit once every 6 or 7 months for 10 years. Each visit will be 2 to 3 |
| Who can participate | * INCLUSION CRITERIA: In order to be eligible to participate in this study, an individual must meet all of the following criteria: * Stated willingness to comply with all study procedures, including fasting at least 10 hours before each blood draw * Stated willingness to refrain from aspirin or non-steroidal anti-inflammatory drugs (NSAIDs) for 7 days prior to any visits * Age \>= 18 years * In good general health as evidenced by self-reported medical history EXCLUSION CRITERIA: An individual who, by self-report, meets the following criteria will be excluded from participation in this study: * Current pregnancy or lactation * Active malignancies known, active known auto-immune disease, known major CVD (e.g., heart attack, stroke, venous thromboembolism, heart failure), severe bleeding hist |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | National Heart, Lung, and Blood Institute (NHLBI) |
| Locations | Bethesda, Maryland, United States |
| Start date | 2026-03-26 |
| NCT ID | NCT07137429 |
| Official listing | https://clinicaltrials.gov/study/NCT07137429 |