Pleth Variability Index for Predicting Low Blood Pressure During Maintenance Hemodialysis
What is this study about? We are studying whether the Pleth Variability Index (PVI)-a simple, non-invasive measurement from a pulse oximeter-can help predict low blood pressure (hypotension) during routine maintenance hemodialysis. Low blood pressure during dialysis is a common and potentially serious complication. Our
| Condition(s) | Hypotension and Shock, Hemodialysis, End-Stage Renal Disease Requiring Haemodialysis, Intradialytic Hypotension |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | What is this study about? We are studying whether the Pleth Variability Index (PVI)-a simple, non-invasive measurement from a pulse oximeter-can help predict low blood pressure (hypotension) during routine maintenance hemodialysis. Low blood pressure during dialysis is a common and potentially serious complication. Our goal is to find out if monitoring PVI can help identify patients at risk, so that early action can be taken. Who can join? Adults aged 18 to 80 years. Patients who have been receiving maintenance hemodialysis regularly for more than 3 months. Those who are willing and able to participate and sign an informed consent form. Who cannot join? Patients with severe heart rhythm problems, severe peripheral circulation problems, or swelling that makes PVI measurement unreliable. Pat |
| Who can participate | Inclusion Criteria: * Adults aged 18 to 80 years. * Diagnosis of end-stage renal disease and undergoing maintenance hemodialysis for more than 3 months. * Able and willing to provide informed consent and comply with study procedures. Exclusion Criteria: * Severe cardiac arrhythmias or significant peripheral vascular disease that may interfere with PVI measurements. * Local edema, skin lesions, or other conditions that prevent accurate PVI monitoring. * History of hemodynamic instability unrelated to dialysis. * Pregnant or breastfeeding women. * Known allergy or contraindication to materials used in the hemodialysis circuit. * Unable to cooperate with study procedures. * Participation in another interventional clinical study within the past 30 days. |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Lead sponsor | First Affiliated Hospital of Wannan Medical College |
| Locations | Wuhu, Anhui, China |
| Start date | 2025-02-01 |
| NCT ID | NCT07022847 |
| Official listing | https://clinicaltrials.gov/study/NCT07022847 |