Post-hysterectomy Vaginal Cuff Prolapse Repair
This study is a randomized controlled trial comparing two minimally invasive surgeries-laparoscopic lateral suspension and laparoscopic sacrocolporopexy-for women who develop vaginal cuff prolapse after hysterectomy. Vaginal cuff prolapse occurs when the top of the vagina loses support after the uterus is removed, whic
| Condition(s) | Vaginal Cuff Complications |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | This study is a randomized controlled trial comparing two minimally invasive surgeries-laparoscopic lateral suspension and laparoscopic sacrocolporopexy-for women who develop vaginal cuff prolapse after hysterectomy. Vaginal cuff prolapse occurs when the top of the vagina loses support after the uterus is removed, which can cause discomfort, bulging, or urinary and bowel problems. The goal of this study is to determine which surgical approach is safer, more effective, and improves quality of life for patients. Women enrolled in the trial will be randomly assigned to one of the two surgeries, and outcomes such as prolapse recurrence, complications, recovery time, and patient satisfaction will be carefully monitored. By comparing these two techniques, this study aims to provide clear guidanc |
| Who can participate | Inclusion Criteria: Women aged ≥18 years. History of hysterectomy (any approach: abdominal, vaginal, or laparoscopic). Symptomatic vaginal cuff prolapse (POP-Q stage ≥ II). Able to provide written informed consent. Willing and able to comply with study procedures and follow-up visits. Exclusion Criteria: Prior sacrocolpopexy or lateral suspension surgery. Active pelvic infection or untreated malignancy. Severe cardiopulmonary or systemic disease that contraindicates laparoscopic surgery. Known allergy to mesh materials used in the procedures. Inability to complete patient-reported questionnaires due to cognitive or language barriers. Concurrent pelvic organ prolapse requiring additional surgical repair beyond vaginal cuff suspension. |
| Ages | 18 Years |
| Sex | Female |
| Lead sponsor | Kanuni Sultan Suleyman Training and Research Hospital |
| Locations | Istanbul, Istanbul, Turkey (Türkiye) |
| Start date | 2025-09-30 |
| NCT ID | NCT07174921 |
| Official listing | https://clinicaltrials.gov/study/NCT07174921 |