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Post Prandial Individual Responses to Different Foods

This study aims to understand why people respond differently to the same foods, especially when it comes to changes in blood sugar after eating. A continuous glucose monitors (CGMs) will be used to observe how individuals respond to specific meals and drinks (e.g., Oral Glucose Tolerance Test, OGTT). By studying these

Condition(s)PreDiabetes, Diabetes Mellitus, Type 2, Healthy
StatusRecruiting
PhaseNA
Study typeInterventional
SummaryThis study aims to understand why people respond differently to the same foods, especially when it comes to changes in blood sugar after eating. A continuous glucose monitors (CGMs) will be used to observe how individuals respond to specific meals and drinks (e.g., Oral Glucose Tolerance Test, OGTT). By studying these patterns, the investigators hope to identify different types of metabolism and see if certain foods or food ingredients (like fiber, amino acids, or vinegar) can help control blood sugar better for specific groups. This research will help lay the groundwork for personalized dietary advice based on a person's unique biology.
Who can participateInclusion Criteria: * BMI (body mass index) \>19 kg/m2 but \< 45 kg/m2 * HbA1c \< or equal to 7.0% while not on antihyperglycemic medications * Be willing to provide written informed consent for all study procedures. * Able to commute to Stanford campus for on-site visits Exclusion Criteria: * recent (\<6mos) CVD (cardiovascular disease) event * active malignancy * kidney/liver disease * pregnancy/lactation * chronic inflammatory disease * eating disorder * bariatric surgery * history of acute pancreatitis * current use of antihyperglycemic, diabetogenic, or weight loss medications * heavy alcohol use * physical activity \>2 hours/day * inability to come to Stanford CTRU (Clinical and Translational Research Unit) for metabolic testing
Ages18 Years to 80 Years
SexAll
Lead sponsorStanford University
LocationsStanford, California, United States
Start date2025-10-01
NCT IDNCT06989164
Official listinghttps://clinicaltrials.gov/study/NCT06989164

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