PRecision biomArker-Guided MAnagement of TuberculosIs Contacts: a Discrete Choice Experime
This study is part of a broader programme of work to develop and pilot a randomised-controlled trial of new tests to identify people who will benefit most from preventive treatment for tuberculosis (TB). The aim of the current study is to explore factors affecting patient decisions to start preventive treatment. The sp
| Condition(s) | Tuberculosis (TB) |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | This study is part of a broader programme of work to develop and pilot a randomised-controlled trial of new tests to identify people who will benefit most from preventive treatment for tuberculosis (TB). The aim of the current study is to explore factors affecting patient decisions to start preventive treatment. The specific objectives are to understand how patients make decisions about preventive treatment initiation for TB (stage 1); and to design and conduct a "discrete choice experiment" survey to further evaluate preferences (stage 2). |
| Who can participate | Inclusion Criteria: * Adults (aged ≥18 years) who have been tested for latent TB infection in routine clinical services, or are eligible for testing. Eligible people for testing include migrants from countries with high TB incidence (entered UK within 5 years), people with recent contact with a person with TB disease, and people eligible for LTBI screening prior to starting immunosuppression or through occupational health testing. Exclusion Criteria: * Unable to provide informed consent. |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | University College, London |
| Locations | London, United Kingdom |
| Start date | 2025-05-22 |
| NCT ID | NCT07024836 |
| Official listing | https://clinicaltrials.gov/study/NCT07024836 |