Premedication on Post-endodontic Pain
The goal of this clinical trial is to compare the efficacy of preoperative administration of alpha-chemo-trypsin, ibuprofen, and acetaminophen in managing post-endodontic pain in patients with symptomatic irreversible pulpitis. The main question it aims to answer is: What is the efficacy of preoperative administration
| Condition(s) | Premedication |
|---|---|
| Status | Recruiting |
| Phase | Phase 3 |
| Study type | Interventional |
| Summary | The goal of this clinical trial is to compare the efficacy of preoperative administration of alpha-chemo-trypsin, ibuprofen, and acetaminophen in managing post-endodontic pain in patients with symptomatic irreversible pulpitis. The main question it aims to answer is: What is the efficacy of preoperative administration of alpha-chemo-trypsin, ibuprofen, and acetaminophen in managing post-endodontic pain in patients with symptomatic irreversible pulpitis? Participants will undergo root canal treatment after premedication. Researchers will compare \[alpha-chemo-trypsin, ibuprofen, and acetaminophen\] to see the intensity of post-endodontic pain. |
| Who can participate | Inclusion Criteria: * Eligibility for root canal treatment Patients diagnosed with symptomatic irreversible pulpitis with normal apical tissue in mandibular molars Exclusion Criteria: * • Patient under any medication or analgesic intake for pain management. * Patients with any systemic health issues * Patient allergies to trypsin-chymotrypsin, ibuprofen, and paracetamol * Pregnancy. * Non-restorable teeth. * Immature roots. * Calcifications. * Resorptions. |
| Ages | 20 Years to 50 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Gulf Medical University |
| Locations | Ajman, United Arab Emirates |
| Start date | 2024-09-01 |
| NCT ID | NCT06671743 |
| Official listing | https://clinicaltrials.gov/study/NCT06671743 |