PREPARE-M 2024 Undergoing Major Surgery: a Pilot Interventional
Study plan to conduct a pilot interventional study to evaluate the impact of a prehabilitation program on physical function and clinical outcomes. The prehabilitation program will include preoperative physiotherapy assessment, nutrition education, exercise instructions, and inspiratory muscle training for patients with
| Condition(s) | Prehabilitation |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | Study plan to conduct a pilot interventional study to evaluate the impact of a prehabilitation program on physical function and clinical outcomes. The prehabilitation program will include preoperative physiotherapy assessment, nutrition education, exercise instructions, and inspiratory muscle training for patients with MIP\<100 cmH2O. Currently, Singapore General Hospital offers the "Prehabilitation for Elderly Frail Patients Undergoing Elective Surgeries (PREPARE)" program, targeting frail patients undergoing major surgery. The primary outcome of the study is the change in physical function, measured by handgrip strength (HGS), from baseline to 3 days before surgery. Secondary outcomes include changes in the 6-minute walk test (6MWT), maximal inspiratory pressure (MIP), and sit-to-stand ( |
| Who can participate | Inclusion Criteria: * Aged over 65 years who are undergoing elective major non-cardiac surgery * Edmonton Frail Score (EFS) of 6 or higher Exclusion Criteria: * Patients who are unable to provide written informed consent |
| Ages | 65 Years to 100 Years |
| Sex | All |
| Lead sponsor | Singapore General Hospital |
| Locations | Singapore, Singapore, Singapore |
| Start date | 2024-08-05 |
| NCT ID | NCT06620588 |
| Official listing | https://clinicaltrials.gov/study/NCT06620588 |