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Prizvalve® Transcatheter Atrioventricular Valve Replacement Study

To evaluate the safety and performance of the Prizvalve® system in patients with severe atrioventricular annular calcification or failed prosthetic atrioventricular valve/ annulus repair.

Condition(s)Atrioventricular Annular Calcification, Failed Prosthetic Atrioventricular Valve/ Annulus Repair
StatusRecruiting
PhaseNA
Study typeInterventional
SummaryTo evaluate the safety and performance of the Prizvalve® system in patients with severe atrioventricular annular calcification or failed prosthetic atrioventricular valve/ annulus repair.
Who can participate1\. Inclusion criteria for patients with severe atrioventricular valve annular calcification: 1. Atrioventricular valve annular calcification with moderate or severe atrioventricular valve disease (stenosis, regurgitation, or mixed); 2. Patient with symptoms, and NYHA Functional Class≥Ⅱ; 3. 18 years and older who is not in pregnancy or lactation; 4. Life expectancy\>12 months; 5. Patient who is anatomically suitable for transcatheter atrioventricular valve replacement; 6. According to the evaluation of the heart team, the patient can benefit from transcatheter atrioventricular valve replacement; 7. The patient can understand the purpose of the trial, voluntarily participate in and sign the informed consent form, and is willing to accept relevant examinations and clinical follow-ups; 8. Pat
Ages18 Years
SexAll
Lead sponsorShanghai NewMed Medical Co., Ltd.
LocationsShanghai, Shanghai Municipality, China
Start date2022-03-09
NCT IDNCT05275088
Official listinghttps://clinicaltrials.gov/study/NCT05275088

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