Proactive Risk-based Optimization & Notifications for Treatment & Outcomes in Head & Neck
Delays between surgery and the initiation of post-operative radiotherapy (S-PORT) in head and neck cancer (HNC) patients are prevalent and associated with worse oncologic outcomes. This pilot study evaluates whether a proactive, automated care coordination system (PRONTO-HN) can improve adherence to recommended S-PORT
| Condition(s) | Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer, Head &Amp;Amp; Neck Squamous Cell Carcinoma, Larynx Squamous Cell Carcinoma |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Delays between surgery and the initiation of post-operative radiotherapy (S-PORT) in head and neck cancer (HNC) patients are prevalent and associated with worse oncologic outcomes. This pilot study evaluates whether a proactive, automated care coordination system (PRONTO-HN) can improve adherence to recommended S-PORT intervals of ≤42 days at the Centre hospitalier de l'Université de Montréal (CHUM). The study is a single-center, quasi-experimental, interrupted time-series design with two phases. Group A (control) includes patients treated before the intervention (using a prospectively maintained database from August 2024 to August 2025). Group B (intervention) includes patients treated with the new coordination system from September 2025 to September 2026. The intervention includes automa |
| Who can participate | Inclusion Criteria: * All adult patients (age 18 or older). * Pathologically confirmed oral cavity or laryngeal squamous cell carcinoma. * Diagnosed from July 2024 to September 2026. * With planned primary intention surgical resection. * With or without adjuvant therapy. * Treated at the Centre Hospitalier de l'Université de Montréal. Exclusion Criteria: * Patients who do not end up receiving surgery. * S-PORT \> 180 days |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | Centre hospitalier de l'Université de Montréal (CHUM) |
| Locations | Montreal, Quebec, Canada |
| Start date | 2025-08-21 |
| NCT ID | NCT07180901 |
| Official listing | https://clinicaltrials.gov/study/NCT07180901 |