Promoting Early Intervention Timing and Attention to Language
The proposed study (PETAL: Promoting Early intervention Timing and Attention to Language) aims to determine the timing of intervention among infants with Increased Likelihood for Autism (ILA; at risk for autism by virtue of having an older sibling with autism) on communication and language outcomes at 24 months. Result
| Condition(s) | MONITOR, COACH |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The proposed study (PETAL: Promoting Early intervention Timing and Attention to Language) aims to determine the timing of intervention among infants with Increased Likelihood for Autism (ILA; at risk for autism by virtue of having an older sibling with autism) on communication and language outcomes at 24 months. Results of this study will determine when (9 vs 12 vs 15 months), and based on which measures (brain, language, or their combination) to augment parental support with a specialized parent-mediated coaching intervention for optimal outcomes on communication and language at 24 months. Children will be recruited at 6-8 months of age and will begin with entry assessments. All children will first begin with the MONITOR condition (using Ages \& Stages Questionnaire (ASQ-3) and activity c |
| Who can participate | Inclusion Criteria: * This study will recruit approximately 140 infants ages 6-8 months of age who are younger siblings of children with ASD. * Both males and females are eligible for study participation and will be recruited. * Family income is under the very low income described under the Department of Housing and Community DevelopmentDivision of Housing Policy Agreement for the city of Los Angeles. Exclusion Criteria: * Infants who have seizures and are not stable on anti-seizure medication * Infant is expected to have surgery over the next year * Infant has associated physical disorders, and/or co-morbid with other syndromes or diseases. * All of the children will be free of additional sensory or motor impairments (e.g., Visual or hearing impairment) and othergenetic syndromes (e.g., D |
| Ages | 6 Months to 8 Months |
| Sex | All |
| Lead sponsor | University of California, Los Angeles |
| Locations | Los Angeles, California, United States; Worcester, Massachusetts, United States |
| Start date | 2024-11-25 |
| NCT ID | NCT05853861 |
| Official listing | https://clinicaltrials.gov/study/NCT05853861 |