Prospective Monocentric Clinical-biological Database
Pancreatic adenocarcinoma (PA) is a solid cancer with a very poor prognosis with overall survival, all stages combined, not exceeding 5% at 5 years. The incidence and number of deaths caused by this type of tumor have been steadily increasing for two decades. In the absence of therapeutic advances, PA will be one of th
| Condition(s) | Pancreatic Cancer |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Pancreatic adenocarcinoma (PA) is a solid cancer with a very poor prognosis with overall survival, all stages combined, not exceeding 5% at 5 years. The incidence and number of deaths caused by this type of tumor have been steadily increasing for two decades. In the absence of therapeutic advances, PA will be one of the leading causes of cancer deaths in 2030. In recent years, researchers and clinicians have now attempted to characterize and understand PA as a whole, through the various stages of its carcinogenesis and the analysis of its microenvironment. Indeed, the stroma of PA can represent up to 80% of the tumor mass and mainly composed of activated fibroblasts (CAF), endothelial and immune cells and extracellular matrix (collagen and fibronectin). However, the characterization of cel |
| Who can participate | Inclusion Criteria: * Patient over the age of 18; * Patient managed for pancreatic adenocarcinoma; * Patient eligible for at least one (or more) surgery (s) and chemotherapy; * Patient giving informed consent Exclusion Criteria: * Patient not affiliated to a social security scheme; * Pregnant and / or nursing patient; * Patient under guardianship, curatorship or safeguard of justice; * Patient whose regular follow-up is impossible for psychological, family, social or geographical reasons. |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | Institut du Cancer de Montpellier - Val d'Aurelle |
| Locations | Montpellier, Occ, France |
| Start date | 2019-05-15 |
| NCT ID | NCT04136132 |
| Official listing | https://clinicaltrials.gov/study/NCT04136132 |