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Psychiatric Symptom Predictors in Methamphetamine-Induced Psychosis

This longitudinal observational study aimed to investigate environmental, familial, and individual factors associated with psychiatric symptom severity in participants diagnosed with methamphetamine-induced psychotic disorder (MP). Participants diagnosed according to Diagnostic and Statistical Manual of Mental Disorder

Condition(s)Methamphetamine Induced Psychosis
StatusRecruiting
Study typeObservational
SummaryThis longitudinal observational study aimed to investigate environmental, familial, and individual factors associated with psychiatric symptom severity in participants diagnosed with methamphetamine-induced psychotic disorder (MP). Participants diagnosed according to Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5-TR) criteria was followed/will be followed prospectively for one year. Sociodemographic characteristics, treatment adherence, perceived social support, addiction-related clinical variables, insight levels, and psychotic symptoms was assessed/will be assessed monthly using standardized psychometric instruments. The study aimed to identify predictors associated with relapse-remission patterns and changes in psychiatric symptoms over a one-year follow-up
Who can participate* Methamphetamine-Induced Psychotic Disorder (MP) Group: \*Inclusion Criteria: * Diagnosis of MP according to DSM-5-TR * Medication-free for at least one month prior to admission * Age ≥ 18 years and \<65 years * Provided informed consent * Methamphetamine-Induced Psychotic Disorder (MP) Group: * Exclusion Criteria: * Hypertension * Diabetes mellitus * Chronic kidney disease * Rheumatoid arthritis * Systemic lupus erythematosus * Cardiac illness * Severe neurological disorders * Immunological or systemic illness * Primary psychiatric disorders other than MP * Alcohol use disorder
Ages18 Years to 65 Years
SexMale
Accepts healthy volunteersYes
Lead sponsorElazığ Mental Health and Diseases Hospital
LocationsElâzığ, Elâzığ, Turkey (Türkiye)
Start date2025-02-03
NCT IDNCT07459257
Official listinghttps://clinicaltrials.gov/study/NCT07459257

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